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How Ciprodex Works, Who Can Use It, and Off-Label Indications

How Does This Medication Work?

Ciprodex contains a combination of ciprofloxacin and dexamethasone. Ciprofloxacin is an antibiotic that belongs to a group of medications called fluoroquinolones, or "quinolones" for short. Fluoroquinolones interfere with a bacterial enzyme called DNA gyrase. This enzyme is needed by the bacteria to make DNA, which is important for the bacteria to multiply.
 
Dexamethasone belongs to a group of medications called corticosteroids. It works to reduce inflammation and suppress the body's natural immune response to infection. By doing this, dexamethasone helps reduce the redness, swelling, and itching that often accompany an ear infection.
 

Can Children Use It?

This medication is approved for use in children six months old and older. Ciprodex has not been adequately studied in children younger than six months of age.
 

Can Older Adults Use It?

Yes -- older adults can use Ciprodex for outer ear infections (otitis externa). However, this medication is not approved to treat middle ear infections (otitis media) in older adults. It is only approved to treat middle ear infections in children who have ear tubes.
 

Is Ciprodex Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend using Ciprodex for something other than otitis media or otitis externa. This is referred to as an "off-label" use. At this time there are no widely accepted off-label uses for Ciprodex.
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Ciprodex Medication Information

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