Cipro HC is approved for the treatment of acute otitis externa, also called swimmer's ear, which is a type of outer ear infection. The medication comes in the form of an ear drop that is applied into the infected ear twice a day for seven days. Most people have no problems when using it, although the most common side effect is headache.
Cipro HC contains a combination of ciprofloxacin and hydrocortisone. Ciprofloxacin is an antibiotic medication that belongs to a group of drugs called fluoroquinolones, or "quinolones" for short. Fluoroquinolones interfere with a bacterial enzyme called DNA gyrase, which is needed by the bacteria to make DNA. Bacteria need to make DNA in order to multiply.
Hydrocortisone belongs to a class of drugs called corticosteroids. It works to reduce inflammation and suppress the body's natural immune response to infection.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Cipro HC [package insert]. Gainesville, GA: Stat RX USA; 2009 October.
Micromedex Healthcare Series [Internet database]. Greenwood Village, CO: Thomson Reuters (Healthcare), Inc. Updated periodically. Accessed November 2, 2010.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed November 2, 2010.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed November 2, 2010.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed November 2, 2010.
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