Meclizine hydrochloride (Antivert®, Bonine®, Dramamine® Less Drowsy Formula) is a medication approved for treating motion sickness and vertigo. It is available over-the-counter (for motion sickness only) or with a prescription (for motion sickness or vertigo).
Meclizine belongs to a class of drugs known as antihistamines. These drugs work by blocking histamine receptors. Meclizine also probably works to alleviate symptoms of motion sickness by blocking acetylcholine receptors (with its "anticholinergic" activity).
This medication comes in tablet and chewable tablet form and is usually taken by mouth once or twice a day. For the non-prescription versions, there is only one standard recommended dosage for this medication. For prescription meclizine products, the recommended dosage will vary, depending on the medical condition being treated.
(Click Meclizine for more information on what meclizine is used for, to learn about the potential side effects of this drug, and to find out what you should discuss with your healthcare provider before starting treatment.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Bonine Original [product label]. Insight Pharmaceuticals.
Antivert [package insert]. New York, NY: Pfizer, Inc.; 2006 October.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed July 8, 2009.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins; 2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed July 8, 2009.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed July 8, 2009.
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