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Taking Meclizine With Other Drugs

Meclizine Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when meclizine is combined with any of the drugs listed above.
 
Alcohol
You should avoid alcohol while taking meclizine, as undesirable side effects (such as excessive drowsiness, dizziness, or confusion) may result.
 
Acetylcholinesterase Inhibitor Medications
Taking meclizine with an acetylcholinesterase inhibitor can make both medications less effective. Your healthcare provider may need to monitor you more closely and adjust your dose of these medications to prevent interactions from occurring. Check with your healthcare provider before combining these medications.
 
Anticholinergic Drugs
Combining an anticholinergic medication with meclizine (which is also an anticholinergic medication) can increase your risk of meclizine side effects, such as dry mouth, constipation, dry eyes, or difficulty passing urine. Check with your healthcare provider before combining these medications.
 
Other Medications That Cause Drowsiness
Check with your healthcare provider before combining meclizine with any other medication that also causes drowsiness, as undesirable side effects (such as excessive drowsiness, dizziness, or confusion) may result.
 
Phenothiazines
It is possible that meclizine may increase the risk of a dangerous irregular heart rhythm (arrhythmia) due to a phenothiazine medication. Additionally, combining meclizine with a phenothiazine increases the risk of excessive drowsiness.
 
Pramlintide
Both pramlintide and anticholinergic medications (including meclizine) can slow down the movement of food through the digestive tract. Taking them together can increase the risk of constipation or nausea. Talk with your healthcare provider before combining these medications.
 

Meclizine HCL Medication Information

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