Meclizine for Motion Sickness

Meclizine hydrochloride (Antivert®, Bonine®, Dramamine® Less Drowsy Formula) is an antihistamine that is approved for several different uses. Some versions of this medication can be found over-the-counter (otc), while others are available by prescription only. You can use both versions of the drug for motion sickness treatment.
 
Both the prescription and non-prescription forms of meclizine are approved for preventing and treating common symptoms of motion sickness, such as nausea, vomiting, and dizziness. This drug is different from many other oral motion sickness medications in that it lasts longer and generally causes less drowsiness.
 
It is generally recommended to take meclizine one hour before embarkation, and to repeat this dosage every 24 hours if necessary. The medicine usually works best if you take it before motion sickness symptoms begin, although you can expect some relief even if you wait until symptoms develop.
 
(Click What Is Meclizine Used for? to find out how the drug works for motion sickness, to learn about meclizine's other approved uses, and for information on whether this product is suitable for children.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD